Despite the importance of Intrinsically Disordered Proteins (IDP), little is known about the binding locations of most targets due to the difficulty of obtaining a crystal structure.

  • The short α-helix often plays an important role in IDP interactions. PepMetics is ideal for modulating such interactions.
  • Predicting the binding sequences of IDPs, PepMetics enables discovery of hit compounds for unknown binding sites involved with IDPs.