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TOKYO, Japan, 28 Nov 2023: –PRISM BioLab, Co. Ltd. , a leading discovery and development biotechnology company designing small molecule inhibitors of protein-protein interaction (PPI) targets, today announced that it has entered into a License and Collaboration Agreement with Eli Lilly and Company. Read Full Press Release
アーカイブ: ニュース
Rational Strategy for Designing Peptidomimetic Small Molecules Based on Cyclic Peptides Targeting Protein–Protein Interaction between CTLA-4 and B7-1
Pharmaceuticals 2022, 15(12), 1506
Tsuihiji, Kumiko; Honda, Eiji; Kojoh, Kanehisa; Katoh, Shizue; Taguri, Tomonori; Yoshimori, Atsushi; Takashima, Hajime
Development of low-molecular-weight compounds targeting the cancer-associated KLF5 transcription factor
ACS Medicinal Chemistry Letters, 13(4), 687-694 (2022)
Nakaya, Takeo; Aizawa, Kenichi; Taguchi, Yuki; Tsuji, Kentaro; Sekine, Sachi; Murakami, Kazuhiro; Kasai, Masaji; Nakano, Hirofumi; Kondoh, Yasumitsu; Dan, Shingo; Yoshimori, Atsushi; Kouji, Hiroyuki; Takehara, Dai; Suzuki, Toru; Osada, Hiroyuki; Marata, Masayuki; Tanaka, Akira; Nagai, Ryozo
PRISM BioLab、大原薬品工業 とライセンス契約に基づくマイルストン達成のお知らせ
TOKYO, Japan, 31 May 2023: – PRISM BioLab, a Japan based biotechnology company with a proprietary peptide mimetic small molecule drug discovery platform, today announced a milestone achievement of a clinical development conducted by Ohara Pharmaceutical Co., Ltd., a Japanese pharmaceutical company that discovers and develops orphan drugs and generic drugs, based on their licensing...
サイクリックペプチド模倣技術を用いたCTLA-4とB7-１のPPI阻害剤創出に関する論文が、PharmaceuticalsのPPI特集号に掲載されました
The paper published in the special issue of Pharmaceuticals journal dedicated to “Small Molecules Targeting Protein-Protein Interactions (PPIs): Current Strategies for the Development of New Drugs” presents a new method to generate small-molecules PPI inhibitors using only a sequence of a binding peptide. Potent and active PPI inhibitor peptides can be readily generated by various...
ファーマインテリジェンス・アワード・ジャパン2022受賞記念ウェビナー『低分子によるPPI阻害：新たな創薬パラダイム』のお知らせ
PRISM BioLab’s proprietary drug discovery platform, PepMetics®, is a technology that enables the control of protein-protein interactions by small molecules with a unique peptide-mimicking backbone, potentially creating a new drug discovery paradigm. In this webinar, Dai Takehara, President of PRISM BioLab, will introduce the PepMetics® technology and share his experiences in managing a biotech startup,...
Informa Pharma Intelligence Award 2022 Biotech company of the year受賞
We are pleased to announce that we have won the Biotech company of the year in the Private category of the Informa Pharma Intelligence Award 2022, the Japanese version of the Scrip Awards, which have been held in the UK for 17 years. Read More | Event Report
PRISM BioLab、製薬大手のRoche社と Genentech社に対し独自開発のペプチド模倣技術を用いた低分子ライブラリーを提供
TOKYO, Japan, 5th Jan. 2022: — PRISM BioLab, a Japan based biotechnology company with a proprietary peptide mimetic small molecule drug discovery platform, today announced it has entered into a multitarget research collaboration and licensing agreement with Roche and Genentech, a member of the Roche Group. Read Full Press Release
エーザイとPRISM BioLab共同創製のCBP/β-catenin阻害剤E7386について、臨床におけるPOC（Proof of Concept：創薬概念の検証）を達成
エーザイ株式会社と株式会社PRISM BioLabは、このたび、両社が共同で創製した中分子化合物であるCREB-binding protein （CBP）/β-catenin阻害剤E7386について、臨床におけるPOC（Proof of Concept：創薬概念の検証）を達成したことをお知らせします。
株式会社PRISM BioLab、エーザイ株式会社より資金調達
PRISM BioLab, the Japan based biotechnology company with proprietary small molecule drug discovery technology ”PepMetics®”, today announced that it has raised ¥100 million in Series C funding through a third-party allotment to Eisai Co. Ltd. on October 14. PRISM has completed the series C financing of 1.4 billion yen in total and aims to achieve...