エーザイ株式会社と株式会社PRISM BioLabは、このたび、両社が共同で創製した中分子化合物であるCREB-binding protein （CBP）/β-catenin阻害剤E7386について、臨床におけるPOC（Proof of Concept：創薬概念の検証）を達成したことをお知らせします。

PRISM BioLab, the Japan based biotechnology company with proprietary small molecule drug discovery technology ”PepMetics®”, today announced that it has raised ¥100 million in Series C funding through a third-party allotment to Eisai Co. Ltd. on October 14. PRISM has completed the series C financing of 1.4 billion yen in total and aims to achieve...

本稿では、ペプチド模倣化合物と実際のペプチドの構造との類似度を評価する手法を開発し、当社の化合物が優位性を示すことが述べられています。
Visualized and Quantitative Conformational Analysis of Peptidomimetics
ACS omega, 6(40), 26601-26612 (2021)

PRISM BioLab, the Japan based biotechnology company with proprietary small molecule drug discovery technology ”PepMetics®”, today announced that it has raised a total of ¥1.3 billion in Series C funding on August 27. Read Full Press Release

PRISM BioLab provides PepMetics® (peptide mimetic small molecules) Technology for generating Hit and Lead compounds against Servier’s novel target. Read Full Press Release

PRISM Biolab provides The PRISM Library, proprietary library of peptide mimetic small molecules for screening against Merck’s novel targets Read Full Press Release

PRISM Biolab provides The PRISM Library, proprietary library of peptide mimetic small molecules for screening against Boehringer Ingelheim’s novel targets Read Full Press Release

PRISM Pharma Co.,Ltd. (“Pharma”) and its wholly owned subsidiary, PRISM BioLab Co.,Ltd.(“BioLab”), have merged as of Octorber 1,2018. BioLab succeeds all Pharma’s rights and obligations. Because those two companies were operated as one by the same management, actual business will not change at all after this merger. PRISM BioLab Co., Ltd. President & CEO Dai...